The CIA was perfectly happy with JFK as President until he screwed them by withdrawing the air support for the Bay of Pigs.
Sam G and all his peers around the country were also perfectly happy getting JFK elected. Hell, they figured he owed them already for enabling his father's riches before delivering Illinois in the election. Sam G was pals with Sinatra, who hung with JFK and his brother-in-law Peter Lawford. Mooney and JFK were even shtupping the same mistress, Judith Exner.
Despite what you may believe, Tricky Dick was never close to being the most powerful man in DC during those times - 50's and early 60's. J. Edgar Hoover had way too much dirt on him.
*MySmiley*
"Bustin' makes me feel good!"
Ghostbusters, by Ray Parker Jr.